Trivia: Game Over: While all the characters in The Simpsons are drawn with four fingers, God is drawn with five fingers, reflecting how he is different from the rest of them.
Trivia: This game offers 16 levels with different 2-character groupings. There are seven levels with Homer and Bart (eight if you count Game Over for the Wii and PSP versions), three with Bart and Lisa, two with Marge and Lisa, one with Homer and Lisa and one with Homer and Marge. However, there are no levels in the game that feature a 2-character grouping between Marge and Bart. The closest the game ever gets to this is the 4-character grouping Game Over (but only for the Xbox 360 and PS3 versions).
Trivia: The Land of Chocolate: When the Simpsons are watching TV, if you listen to the TV, you'll hear that an advert for the game Grand Theft Scratchy is playing. Grand Theft Scratchy ends up being a part of the plot later in the game.