Revealing mistake: When Nica goes to investigate the screams in the first part of the movie, as she opens and closes the door she appears to be moving in a way that implies she is standing and not sitting in her wheelchair, this completely contradicts her being a paraplegic.

Curse of Chucky (2013)
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Directed by: Don Mancini
Starring: Brad Dourif, Alex Vincent, A Martinez, Danielle Bisutti
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Trivia: The appearance of Charles Lee Ray on-screen during the flashback sequences marks the first time that Brad Dourif had appeared in human form in one of the "Chucky" films since the original. (Although photos of him from the original did subsequently appear in the other sequels, he had not shot any new live-action material in 25 years).
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Answer: The films don't delve into either Chucky or Tiffany's backstory, and the films themselves are the only official canon. So until it is properly addressed in the movies, it's basically up to your imagination.