Continuity mistake: When Ash & co. are in the boat with Team Rocket (who's dressed as Vikings), watch Brock's shirt sleeve (The one away from Misty) when Misty puts Togepi inside her knapsack. It goes from a dark orange to green (the same color as Brock's vest) for a few frames before turning back. (00:33:26)
Continuity mistake: When Fergus goes to Gyarados after Mewtwo reflects its Hyper Beam, you can see the back of a Nidoking, but Fergus has a Nidoqueen. (00:43:23)
Character mistake: When "If Only Tears Could Bring You Back" appears in the retyped ending credits of the English dub, Mewtwo Music is misspelled as "MewTwo Music" and "Newtwo Music" with courtesy misspelled as "couresy." Also, Lissome Music is misspelled as "lissome Music" with Connotation Music misspelled as "connotation Music." (01:13:33)
Other mistake: When "Catch Me If You Can" appears in the retyped ending credits of the English dub, Brian M Steckler has his first name misspelled as "Briand." Also, Lava/Atlantic Records is misspelled as "Lava/Atlantic records." Additionally, Blessid Union of Souls is misspelled as "Blessed Union of Souls." (01:13:24)
Other mistake: When "We're A Miracle" appears in the retyped ending credits of the English dub, Todd Chapman's surname is misspelled as "Champan." Also, RCA Record Label is misspelled as "RCA record Label." (01:13:29)
Other mistake: When Giovanni says, "Learn to use them to accomplish your purpose," Mewtwo's left arm is missing. Also, there are no cables connected to the back of the left shoulder piece of its armour, but in the next shot, there are. (00:17:03)
Factual error: When New Island's reflection is in a window on Giovanni's helicopter, it is not reversed. (00:15:19)
Continuity mistake: When Officer Jenny speaks after Fergus puts his right foot forward, the clothes and accessories of some people change. (00:31:08)
Continuity mistake: When Ash says, "Wow!" the bowl of fruit changes as well as a cup changing from being on right of it to the left of it. (00:40:25)
Other mistake: In the first part of the retyped ending credits for the English dub with songs, published is misspelled as "publisher" with produced misspelled as "producerd." Also, Cherry River Music Co. Is misspelled as "Cherry River Kusic Co." Additionally, Elektra Entertainment Group is misspelled as "Elektrica Entertainment Group." (01:13:19)
Other mistake: When the copyright message appears, the sentence below reads 'The events, characters and firms depicted in this motion picutre and ficitituious', misspelling the words 'picture' and 'fictitious' and using 'and' in place of 'are'. In the same shot, Ash's hat turns completely red. (01:13:52)
Other mistake: In the retyped ending credits of the English dub, one of the sections is titled "Main Title Animation - 'MewTwo Strikes Back'", but incorrectly formats Mewtwo as 'MewTwo'. Shortly after, under 'Japan Production', OLM, Inc. and Shogakukan Production Co., Ltd. are credited twice. (01:11:19)
Other mistake: In the retyped ending credits of the English dub, one of the sections is titled 'Chief Animatior', but spells animator as 'animatior'. Shortly after, Anime World is spelled as 'Animaworld'. (01:12:46)
Other mistake: In the retyped ending credits for the English dub, during the shot of Ash and his friends watching the sunset, many sections previously listed in the credits are listed again, such as 'Animation Camera Shooting Staff' and 'Foley Artist', including many of the same individuals and companies. Additionally, later in the same shot, Continental Far East Inc. and Tokyo TV Center are misspelt as 'Continental Fal East Inc.' and 'Tokio TV Center', respectively. (01:12:58)
Continuity mistake: In Ash and his friends' first appearance, the cream and orange stripes on Ash's bag turn green. (00:21:08)
Revealing mistake: When Misty speaks after first showing a closeup of Ash, Brock's right arm is not drawn completely. (00:21:21)
Other mistake: When Ash and friends enter the ferry terminal, the inner part of a Raichu's left ear is mistakenly coloured brown instead of yellow. Also, the boy thinking about something has a yellow shirt which turns white in the next shot. Additionally, the boy across from him has a white shirt, but in the next shot, it is blue. (00:30:01)
Continuity mistake: When Misty retrieves the white card, the marks on Ash's cheeks go from present to absent. (00:27:35)
Revealing mistake: When Mewtwo is first seen in a tower, its right hand and the upper half of a woman's body are translucent with the screen showing through them. (00:25:56)
Continuity mistake: When first showing a closeup of Ash, a plate next to the centre of the table goes from present to absent. (00:21:19)
Suggested correction: As explained in the DVD commentary, Team Rocket don't know everything about Pokemon. They thought it was an Alakazam though.