Continuity mistake: In the opening scene at the Arctic Circle, two of the workers are shown playing poker. The player on the right pushes the coin pile to the left side of the container. A couple of shots later, after the player on the left has claimed victory, the coin pile has suddenly moved to the middle. (00:01:35)
Continuity mistake: When Gru is making balloons with his balloon gun thing he attaches an inflated unicorn balloon to the door frame and an exterior shot of the front lawn is shown. This shot shows a playhouse on the right hand side of the lawn. Later on, when Lucy arrives at the house, the playhouse is no longer on the lawn. (00:03:30 - 00:07:45)
Continuity mistake: In the scene where Gru first meets Lucy Wilde, Gru takes out his freeze ray and fires it at Lucy. Lucy stops the freeze with a flame gun thing and then she walks over to him and tazes him. Gru then drops the freeze ray, but it disappears when she goes to put Gru in the boot of her car. (00:08:30)
Continuity mistake: When Doctor Nefario is having a send off, he begins to blast off in his scooter very slowly. The shot after he says "This may take a while", the Minions begin to leave the area, yet in the next shot, the other Minions have vanished completely. There was nowhere near any time for them to have left the area that quickly. (00:21:10)
Continuity mistake: One of the minions is shown dressed as a maid hoovering the floor. The hoover continues to move along the floor after the minion answers the door. The hoover is shown moving past the door. But when the next minion is shown, the hoover is now shown only just going past the door. (00:21:45)
Continuity mistake: When the Minion dressed as a maid answers the door, there is nothing next to it. When the shot returns to the door after the Minion has been taken, a umbrella and a holder for the umbrella have suddenly appeared. (00:21:50)
Continuity mistake: At the mall the double escalator in front of "Eagle Hair Club" appears and disappears several times between shots and scenes. (00:24:55 - 00:41:05)
Continuity mistake: The Mexican flag on El Macho's chest vanishes after the bakery scene. (00:27:30 - 01:06:15)
Continuity mistake: When Gru follows Eduardo through the corridors, he stumbles to find him dancing along a floor key pad to unlock the lift. It is also shown that if a key is pushed incorrectly, the key turns red and a weapon is launched at the person on the key pad. When he begins to activate the key pad, the first key he steps on is the key second to the left on the first row and continues the rest of the pattern. Gru then attempts to do the exact same sequence. The first key he steps on is the key second to the left on the second row, despite the fact that Eduardo actually triggered the first sound effect with the key on the first row, second to the left. Despite this, the sound effect is still correctly triggered. (01:03:40)
Continuity mistake: As soon as Eduardo finishes activating the floor key pad, he is shown standing half way between the start and the end of the floor key pad. Next shot, he is suddenly a few steps away from the end of the pad. (01:03:45)
Continuity mistake: After watching El macho activate the dance floor key to the lift, Gru then does the same thing. During the first attempt, Gru spills guacamole on the floor, his nacho hat gets sliced in half and more guacamole falls. He then throws the nacho hat to one side and tries again. But in the shot from above the guacamole on the floor has vanished. (01:04:10)
Continuity mistake: When Gru is attempting to unlock the floor key pad, he triggers an incorrect key and some fire is blown at him. Some smoke is left all over his face. Gru triggers another incorrect key and some darts are launched at him. The smoke is still there, but as he falls over, most of the smoke on his face has gone. The smoke on his right cheek is still there, but has still vanished from his face. (01:04:20)
Suggested correction: I watched the scene carefully. The smoke stains stay there the entire time. When he falls they are perhaps a bit fainter, but still there. When he walks into the elevator and turns toward the camera is very hard to say if all the stains are there or not due his wide smile, and that's only if you pause it.
Continuity mistake: When the elevator door opens to show El Macho's lair, Gru walks out and there is no-one in sight. A few shots later, El Macho has suddenly appeared behind Gru. There was no space behind Gru that El Macho could have hid behind. (01:06:00)
Continuity mistake: El Macho says that the volcano he was going to launch Lucy into was the same volcano he faked his death in earlier, but his volcano was in a large landscape, while the volcano Lucy and Gru went to was on a little island. (01:19:35)
Continuity mistake: When Tom the Minion dressed as a maid is hoovering, he answers the front door by opening it towards him as does the minion who looks out of the door after Tom has been taken. In the scene with Gru sat on the steps in the rain, sad that Lucy is off to Australia, Agnes comes out with an umbrella, but now the door opens outwards.