David: Big things have small beginnings.
Meredith Vickers: A king has his reign, and then he dies. It's inevitable.
Meredith Vickers: Good morning. I am Meredith Vickers, and it is my job to make sure you do yours.
Janek: There's a ship. They're leaving.
Elizabeth Shaw: To go where?
Janek: Earth.
Peter Weyland: To those of you who know me: you will be aware by now that my ambition is unlimited. You know that I will settle for nothing short of greatness, or I will die trying. To those of you who do not yet know me: allow me to introduce myself. My name is Peter Weyland, and if you'll indulge me, I'd like to change the world.
Elizabeth Shaw: My God, we were so wrong.
Answer: It's a matter of opinion, but watching the first Alien film gives enough of the necessary back story to understand Prometheus. However, it's possible to watch and understand Prometheus without seeing any of the other four Alien films. I would only recommend watching Alien 1 and 2.
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