Continuity mistake: The main character portrayed by Bruce Willis walks out of the elevator with his jacket buttoned up, but crooked. (It's buttoned up wrongly.) In the next shot it's back to its proper self again. (00:17:10)
Visible crew/equipment: In one shot at the end, when all the surrogates fall to the ground, you can see a few crew members (one with a white megaphone) standing in the street in the upper left corner. (01:19:55)
Continuity mistake: During the car chase the damages on the car differ in every angle. The copilot door's glass, for example, swaps from being slightly broken, to totally shattered, then perfect, then it's gone, then it's slightly damaged.
Continuity mistake: When Willis's surrogate is lying on the ground with a woman pointing a rifle at him, the collar on his shirt swaps from being away from the face to up and very close, between the wide and close-up angles.
Plot hole: The character Strickland (played by Jack Noseworthy) is born in 1969 (according to his file in the FBI computers that Peters accesses), like Noseworthy himself. Since the character is presumably also approximately 40 years old, this would imply that the film takes place in 2009, which is totally inconsistent with the level of technology needed for surrogacy.
Continuity mistake: At the end of the movie Willis arrives home looking for his wife. There's a close-up of a yellow bottle surrounded with pills. Its position and the amount of pills changes in the wide angle.
Factual error: In the beginning of the movie, during the "news" clips, it is stated that the Dreads have reservations near major cities. They show a map of North America, and have indicated some places in Canada that have reservations. Unfortunately, most of the locations shown are not near any major cities, and in fact most shown are in the middle of nowhere. The vehicles throughout the movie are current to modern day, not even showing any new models that were released in 2010, so it is safe to assume the movie takes place in the near future. It is not at all conceivable that major cities in Canada would spring up in the next few years for the locations shown on the map.
