Deliberate mistake: When Agent Hoffman writes the letter to Amanda, he puts the envelope so her name is pointing down, yet when Amanda opened this drawer in Saw III her name was at the top. The director had to do this or it would have revealed Hoffman was the new apprentice all along.

Saw IV (2007)
1 deliberate mistake
Directed by: Darren Lynn Bousman
Starring: Tobin Bell, Betsy Russell, Costas Mandylor, Scott Gordon-Patterson, Scott Patterson
Other mistake: In Saw II, Jigsaw shares a story with Detective Matthews about how he attempted suicide after his cancer diagnosis by driving his car off a cliff. We then see Jigsaw pulling a metal rod out of the left side of his stomach. However, no puncture wound/scarring is visible on Jigsaw's stomach when his autopsy is being performed. (00:00:50)
Agent Strahm: We're here to find the person helping Jigsaw and Amanda Young.
Question: A glass casket with a key inside it is shown in John's warehouse. What does that mean?
Answer: This was revealed by director Darren Bousman to have originally been used in a now-deleted (and not released as of Oct. 2020) scene in the movie. The glass box is used for what is (most likely) a different purpose in Saw V.
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Answer: It plays an important role in the next few movies.