Plot hole: In any given volume of air, there are any number of tiny, living organisms; dust mites, viruses, bacteria, etc. Why did the teleporter combine Seth's DNA only with the fly that was in the chamber? If he had taken the "floating organisms" into account in his calculations and programming, then why would he not have excluded ALL foreign DNA?
The Fly (1986)
Ending / spoiler
Directed by: David Cronenberg
Starring: Jeff Goldblum, Geena Davis, John Getz, Joy Boushel
Jeff Goldblum once again goes into the teleport machine. He comes out transformed into a hideous creature. Geena Davis blows his head off with a shotgun.
Cronenberg
More mistakes in The Fly
Seth Brundle: I think you're making a mistake. I think you really want to talk to me.
Ronnie: Sorry, I have three other interviews to do before this party's over.
Seth Brundle: Yeah, but they're not working on something that'll change the world as we know it.
Ronnie: They say they are.
Seth Brundle: Yeah, but they're lying. I'm not.
Trivia: The film's director, David Cronenberg, has a cameo in this film as the doctor who helps Ronnie deliver her maggot baby.
More questions & answers from The Fly
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Suggested correction: Just because a character doesn't do something that they probably should/could have, it doesn't make it a plot hole. It's arguably a character error.
The correction makes no sense. If the teleporter included the fly's DNA, it would also have included the DNA of - literally - trillions of bacteria, viruses, mites, etc., etc., that are in and around Seth's body. You cannot have it both ways.