Continuity mistake: When they pick up Warren on the stagecoach, the second shot from inside has the wrong direction of landscape outside, so it seems that Warren changed from the front to the back row.
The Hateful Eight (2015)
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Directed by: Quentin Tarantino
Starring: Samuel L. Jackson, Kurt Russell, Tim Roth, Channing Tatum, Jennifer Jason Leigh
Genres: Western
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Major Marquis Warren: Move a little strange, you're gonna get a bullet. Not a warning, not a question...a bullet.
Trivia: Towards the end of the movie. When Major Marquis runs out of ammo, in the slow motion scene. The score is taken from John Carpenter's "The Thing", another movie staring Kurt Russell.
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Answer: It's not PURELY fictional, as plenty of poisons lead to vomiting and bleeding (cyanide, arsenic, etc.), but Tarantino, as is his wont, definitely takes some artistic license and kicks it up several notches for dramatic/gross-out effect.