Factual error: The open credit sequence takes place at the Atlanta Airport (Hartsfield Jackson), signs are throughout the Delta terminals, Boston Airport announcements are dubbed in until we see John Cusack come off the airplane.
Factual error: There would be no room for a thumb drive inside of a real Rubik's Cube due to the way they are constructed. When dismantled, the individual moving parts are quite small. It would certainly be possible to construct a facsimile of a Rubik's Cube that would have enough room, but it wouldn't be a fully functional puzzle the way it was in the film.
Factual error: The 5th Amendment to the Constitution simply states that "No person... shall be compelled in any criminal case to be a witness against himself." There is no actual or implied provision that means once you have answered a question, you can't plead the 5th on any subsequent questions, as the movie depicts.