Character mistake: In a shot that flashes by very briefly, a London newspaper's headline is shown: "Sherlock Holmes Aides Police." "Aides" should be "aids".
Character mistake: Paul Walker is told of a 240SX with an illegal mod. You then see it is an S15. There was never an S15 240SX. It is a Japanese spec 200SX, chassis code S15.
Character mistake: When discussing the new Pope's name (Luke) at the end of the film, Langdon says: "There have been many Marks and Johns, but never a Luke." In fact, though there have been 23 Pope Johns, there has only been one Pope Mark - reigning for 9 months in 336.
Character mistake: Candy's full name is Candace Washington, which is referred to in the movie, yet when she is released early from prison, the correction officer calls her Candace Collins.