Trivia: Choke author Chuck Palahnuik can be glimpsed in the final scene sitting next to Sam Rockwell on the plane.
Trivia: The name on the delivery van Floss and The Octopus arrive in is "Ditko's Delivery." Steve Ditko is a hall of fame comic artist known for creating Doctor Strange and co-creating The Amazing Spider-Man. In 1994 he was also inducted into the Will Eisner Award Hall of Fame. Will Eisner is the creator of The Spirit comics.
Trivia: Both Frank Langella and Michael Sheen played their respective roles in the original Broadway production.
Trivia: The number Emily gives Will is 212-664-7665. Unlike the usual fake "555" number often used in movies, this is a real number that's also used in Scott Pilgrim vs. The World and The Adjustment Bureau. Universal Studios acquired it precisely to save having to use a fake number in their films.
Trivia: In real life, Georgiana was only nine years younger than her husband, the Duke. She was seven years older than Charles Grey. The film portrays her as being much younger than her husband and closer in age to Charles.
Trivia: Clint Eastwood's son Scott Eastwood makes an appearance in this movie as Trey, the kid she was walking with when they get harassed by 3 men.
Trivia: Despite her prominent billing, Dianne Wiest does not appear until an hour and twenty minutes into the film, and has less than ten minutes of screen time.
Trivia: At one point during the movie, Max visits a storage yard. The name of this yard is "Gognitti Storage". This is a reference to Vinnie Gognitti, who was an important character in the video game series.
Trivia: Some details are taken from Jason Segel's life. For example, the naked breakup is based on a similar incident and he was working on a puppet-based Dracula rock-opera.
Trivia: Elliot's line, "Be scientific, douchebag" was ad-libbed by Mark Wahlberg.
Trivia: Julia Roberts, who plays Michael's mother, Lisa Taylor, is only nine years older than Ryan Reynolds.
Trivia: Ryan Reynolds and Emily Mortimer play the parents of Elisabeth Harnois in this film. In real life, Reynolds is only three years older than Harnois, and Mortimer is only eight years older than her.
Trivia: In real life, Mary secretly married her second husband, William Stafford, while Anne was still Queen. Henry and Anne did not approve because Stafford had a low social rank and little money. Mary was banished from court, and her parents and uncle disowned her. Her final interaction with Anne was probably when Anne sent her a golden cup and some money, but still would not allow her at court. She was probably not present at the execution of Anne, like in this movie.
Trivia: The opening scene really was filmed in one shot with no breaks in filming; they rehearsed and had a run-through five times to get it right.
Trivia: Hulk Hogan claimed he was offered the lead role in this film, which director Darren Aronofsky has disputed. Randy the Ram appears to be partially inspired by Hogan, given he was a megastar in the 80's, has bleach-blonde hair and a tanned skin complexion, and occasionally calls people "brother."