Factual error: When August sits down at the piano in the church and begins to play, he plays a passage of ascending notes (his hand is actually on camera so you see it move to the right, up the piano). However, the audio that you actually hear is a passage of descending notes.
Continuity mistake: When Eli enters Daniel's office, as he goes to sit down his hand move from in his lap, to his side, then back again.
Factual error: Hannibal makes a bomb using latex gloves that were not in use during the early 50's when the movie takes place. (01:28:35)
Continuity mistake: When Nick and Annie are lying together in the hospital bed the camera switches between them a few times, every time Annie's head is either closer to Nick's than it was in the last shot or farther away than in the last shot.
Continuity mistake: The amount of sacks by the oven that Laura moves away keeps increasing and decreasing randomly all the time.
Continuity mistake: When Nikolai is sitting in the chair in the brothel, his jacket sleeve is pulled up to his elbow. When Kiril pulls Nikolai to his feet, the sleeve is pulled all the way down. (00:34:00)
Continuity mistake: Francis' bandages change from shot to shot. Example: When they first leave their compartment on the train to go get a drink, they make their way along an aisle. When Francis says "I want you both to know it", the blue pad is visible over his right ear, but the shot changes as he turns around to say "I love you, Peter." and the blue pad is completely hidden under the white vertical bandage. (00:05:35)
Factual error: There are a number of computers and gadgets shown which were not introduced in early 2002, i.e. HP LaserJet 1320 Printer at Asra's place, HP Color LaserJet shown at the consulate, Acer Notebook used in investigation, and the Nokia 1100 cellphone used by Captain.
Factual error: In the beginning of the film, a variety of different suitors are presented to Elizabeth. Amongst them are Eric XIV of Sweden, reportedly "still madly in love [with her]". Even though he was born the same year as Elizabeth; when this film takes place, in 1585, he had already been dead for 8 years.
Continuity mistake: When the guy and girl are sitting in the car, they put the newspaper with duct tape up on the window but later on both the duct tape and newspaper are gone.
Continuity mistake: In the scene where Tom Cruise show the map of Iran the folder disappears and then reappears on the desk.
Factual error: The Commissioner's secretary, a police constable, wears a shoulder number consisting of four digits only. Metropolitan Police constables' shoulder numbers always have two letters above three digits.
Revealing mistake: During the film, the Nike tick on the Arsenal shirt is a reversed tick, revealing a flipped shot.
Visible crew/equipment: When Gina says she's leaving home, there's a metal ball behind her. On the top right corner a stage light is reflected.
Continuity mistake: In the beginning of the movie, Rachel lies down in the shade of a billboard on the side of the road. When they cut to the wide shot the shadow of the billboard is on the opposite side so Rachel is in sunlight. This might have symbolized the passing of time, but in the next shot, when Harlen comes to wake her, she is in the shade again.
Continuity mistake: At the beginning, the undercover cop says the combination is 666. But the lock has a 4 digit combination.
Visible crew/equipment: You can see a member of the crew walk by inside Monk's house when Elizabeth and Monk are sitting outside of his home talking about their future plans together.
Factual error: When challenged by Henry Lowe, Professor Tolson begins to recite the infamous William Lynch speech. However, the speech was proved to be a hoax that was actually written in the 1990s. No text could have existed at the time of this scene for Tolson to quote.
Revealing mistake: By the end of the movie, when Jamie Foxx is holding the dying Arabian cop, you can see that Jamie's neck injury looks extremely false.
Factual error: In a couple of scenes, most notably the one where Graysmith drives his kid to school, there are newer cars in the background than the year it is supposed to be. In this scene the car is a 1971 Chrysler, when the scene takes place in 1969.