Trivia: Alison Lohman, who plays Nicolas Cage's teenage (14) daughter, is actually 24.
Trivia: The doctor who tells the family Hub checked himself out of the hospital is Eugene Osment, Haley Joel Osment's father.
Trivia: One of B-Rads friends Mocha, who is played by Nick Swardson, is actually one of the writers for the film.
Trivia: After the girl kills herself the gas station they stop at from the outside looks identical to the gas station in the original. (00:14:50)
Trivia: When Burnett and Lowrey take a car to chase the van, the driver is American footballer Dan Marino. The driver of the red and white car who stops and calls Burnett a freak is the film's director Michael Bay. (01:22:35)
Trivia: The Spierig bros. went to their butcher and bought rotten chicken and pig guts to enhance the effects.
Trivia: Never in Oscar Wilde's story was Dorian Gray invincible, as is depicted in the film. Nor did looking upon his picture kill him. Dorian regularly stood in front of the painting, observing the degradation of his soul. He was only killed when he tried to destroy the picture.
Trivia: If you look closely with time-frame advance during the pigeon scene you will see a fish "flying" into a window instead of a pigeon. (00:08:35)
Trivia: Small children have told Billy Bob Thornton they like the film - he was reportedly "stunned" that parents would allow their kids to watch it.
Trivia: The Missing is among very few mainstream films to feature authentic Apache language spoken.
Trivia: After Natalie shoves the 'ice cube' down Brinkman's throat, during the following melee, when Ronica Miles kicks one of Brinkman's men over the balcony the famous "Wilhelm" scream is heard as he falls.
Trivia: Director Tommy Wiseau shot the film using a dual camera-rig. He shot the film on both a 35mm film camera and an (at the time) new HD movie-camera, both mounted to the same rig so they could more-or-less get similar angles, as he didn't quite understand the differences in the mediums and wanted to experiment shooting the film with both simultaneously.
Trivia: This is the first movie Jackie Chan uses special effects for his fighting.
Trivia: During the closing credits the song played is "La Vie en Rose" sang by Jack Nicholson.
Trivia: Just something to look for: in the scene when Gwenyth Paltrow goes to see Mike Myers about how she thinks her test scores were messed up, she asks him if she can retest and he says, "That's not procedure." The shot then goes back to her and you can see a plaque on the wall that says "That's Procedure."
Trivia: In the baseball scene, Rudolph Giuliani yells, "You can do it!" which is a regular line in Adam Sandler films. Rob Schneider says it in The Waterboy, and then again in Little Nicky. Sandler himself says the line in Schneider's The Animal.
Trivia: Bitsey and the intern are staying at the Randolph Motel. Randolph is the last name of the writer of the movie.
Trivia: Any viewers outside of Britain might not get the joke when Billy Mack isn't sure which one is Ant or Dec. They are very well known in the UK, and dominate Saturday night telly. The joke refers to the fact that even though they are popular, a lot of people don't know which one's which.