Plot hole: Had one or more locomotives coupled onto the real runaway's front engine, or even just been pushed by it, anyone aboard the "rescue" engine could have just walked to the unoccupied ones and shut them down - no copters or fireballs required.
Character mistake: After Pookie is killed (with his eyes open) and the bomb is strapped to him, he blinks his eyes.
Other mistake: Interior Minister Roger Frey advises Commissioner Lebel that all members of the police, military and other security forces attending the ceremonies on the day the Jackal is expected to strike will be issued with lapel badges at the last moment, in case he is going to try to masquerade as one of them. We see hundreds of such people in the next part of the film, including Lebel himself and the CRS private who allows the heavily disguised Jackal through the barricades around the site of the ceremony DeGaulle is due to attend. Only the CRS private wears a lapel badge. Not one of the other police or military officers in attendance is wearing a lapel badge of any kind. (01:58:15)
Continuity mistake: In the beginning, when Anderton arrests the jealous husband, he notes that he is being arrested on April 22 - that day - for the future murder of his wife and her lover. Later, while Anderton is jogging, we see billboards advocating a "Yes" vote on pre-crime on April 22. The next day, Anderton's boss Lamar notes that the vote is in a week, which would make it April 15, making the day that the jealous husband was arrested April 14, not April 22. (00:13:05 - 00:15:15)
Continuity mistake: In the end, when the President is visited by the X-Men, he receives a blue binder, which is laid in front of him on the table. When they have left, you see a shot including the President's desk, and you can see that the only thing he has on the table are some sheets of paper, stapled in the upper left corner, opened up. Then the shot changes to a close-up of the President, and then back again, and you see the blue binder in front of him, closed, and the papers have disappeared. (02:01:40)
Factual error: When we see the burning 'DD' in Joe Pantoliano's glasses it is not a reflection. The DD should be backwards in his glasses. (00:26:55)
Continuity mistake: Hooper wears rimless eyeglasses, with the arms either attached at the upper corners of the lenses or at the sides of the lenses. If this didn't happen between shots within the same scenes, it could be presumed that Hooper has two different pairs of glasses and switches between the two, but they do indeed change between shots, such as when Mrs. Kintner slaps Brody, or even later, on the Orca. (00:36:05)
Audio problem: After the aeroplane crashed, a dinosaur stepped over it and the windows shattered making the typical sound of made-of-glass things when broken. They are made of plexiglass (a sort of fibrous plastic).
Continuity mistake: When Norman is getting ready to test himself, he lies down on the bed, fastens himself in and the doctor goes to the computer. However, when it shows him being brought in to the chamber he has several electrodes connected to his chest and head. (00:15:20)
Suggested correction: At first the electrodes are beside Norman's head. While the doctor is fixing him in place, at one point camera focuses on his face. Later when he's stepping back for the PC, the electrodes can actually be seen stuck on his body. You can see them if you have an HD copy. So the camera focusing on his face is indicating that the doctor's doing whatever necessary for the process.
Factual error: Basic physics - Hancock throws Michel from a dead stop to above cloud level in about eleven seconds. The clouds are bog standard cumulus which form at around 7,000 metres in temperate zones. This means that Michel accelerates to about 700 metres per second instantly, from a dead stop. Obviously he cannot accelerate during his ascent, so his starting speed has to be at least that. (In fact he would have to start his ascent much, much faster than 700 metres per second as he would be constantly decelerating due to gravity and air resistance, but it will do as a start point.) Michel accelerates from 0 to 2,520 kilometres per hour - twice the speed of sound - in zero seconds. He would be accelerating at around 5000 Gs, turning him into a very long streak of fine, pink mist.
Continuity mistake: When John and Catherine are in the hangar at the runway, the Cessna's tail number is N3035C. When the plane is shown in the air, the number is N3973F. When they land, the tail number has changed back to N3035C. (01:22:25 - 01:25:50)
Plot hole: The fact that a five minute timer starts after the three Cerberus codes are entered defeats the purpose of the program. If they program was made to destroy their own nuke warheads in case of a misfire you would expect them to be destroyed as soon as all three codes are in. (01:38:20)
Revealing mistake: When Carl is being dragged away by the demons, you can see the cable line that he's attached to. May be fixed on DVD.
Visible crew/equipment: After burning the car, when Dave takes the trash out there is a camera operator at the end of his driveway. (01:11:00)
Other mistake: When Ace rescues the dog and replaces it with a toy dog, the toy dog is in an impossible position. Ace had to place it there when the door was still open, but if the door was closed after that the man would have knocked it over. (00:03:25)
Plot hole: Why on earth would the military be interested in a soldier (pilot, sailor, marine, whatever) who has to go into combat naked and unarmed, and who is detectable by an enemy equipped with a pair of cheap, mass-produced goggles? How would you treat them if they were injured? They would be utterly useless in any form of military operation, even espionage.
Suggested correction: Presumably the military are interested because Sebastian's research could lead to advanced forms of invisibility technology, such as the ability to turn materials and weapons invisible for use in combat.
You cannot second guess the film like that. Sebastian is making no effort to make non-living items invisible and throughout the film we see that is not possible (why else would Sebastian have to walk about naked?). His research is on animals (and later humans) not "materials and weapons" and is based on their physiology, anatomy and metabolism. How would you inject a rifle or a tank with a serum? They don't have a bloodstream. The military wouldn't see any value at all in this research - maybe they would be interested in invisibility, but not if it was restricted to living creatures as we see here.
You know how easy it would be for an invisible person to infiltrate an enemy's compound undetected and take out powerful leaders or dictators? Especially if no-one knew the technology existed.
Easy? Impossible. First, they would be naked and unarmed. Too bad if you are trying to knock off Vladimir Putin - a taekwondo black belt - with your bare hands during a Moscow winter! Being invisible doesn't mean you can avoid making a sound or triggering a pressure plate or an infrared detector and so on and so on. Final answer - a naked, unarmed combatant would be about as useful as a chocolate teapot in any form of operation, covert or otherwise.
Continuity mistake: Throughout the entire film the tattoo on George Clooney's neck moves position and changes shape.
Character mistake: Jim Sturgess uses a sentence that contains the word 'me'. He is corrected, being told that the word 'I' would have been correct. However, he was grammatically correct in his use of the word 'me'. The correction was in error.
Continuity mistake: When they finally arrive at the bottom of the sewer, Eddie's bandage is on a different cheek. (01:59:00)
Revealing mistake: In one shot when the boat is pulling away from the waterfall, you can clearly see that the shot is the same one they used earlier in the movie. The water from the waterfall now is going up the cliff! They have just put it in reverse.
Suggested correction: Not necessarily. Some engines may not have a rear cab access (like Frank/Will's engine had). And even if the rescue engine did have a rear cab access 777's engine only had a side access stair which at the speed it was going is more difficult to climb over from the engine in front of it.
Actually 777's catwalk goes across the front, from side stair to side stair, but someone would have to leap over a rail or a chain to get onto it from the other engine. Why would there be stairs on the right side unless there was a catwalk to get to the door on the left side?