The Hustlers News of the Day - S3-E5
Factual error: They plant Albert's hair on a brush used by the Queen Mother in order to have a DNA sample taken from it match that taken from a hair plucked out of his head by Francis Owen, their mark. The Queen Mother's (non-existent) son would not have the same DNA as her. It could be used to establish a biological relationship but it would not be identical - it could not be. First, Albert's DNA is identifiable as that of a male. The lab testing the sample supposed to be the Queen Mother's would see that immediately. Second, a son's DNA is not identical to either of his parents or his siblings (if any) - it is at least 50% different. Any lab worth their fee would realise in a second that the two samples were from the same person. Another problem - Owen plucks the hair from Albert's head and Stacie handles the hair from Albert she plants on the hairbrush with bare fingers, in both cases hopelessly contaminating the samples with their DNA. The tests really are that sensitive.
The Hustlers News of the Day - S3-E5
Factual error: The laboratory technician uses a bog standard light microscope to match the two DNA samples, one from Albert and one allegedly from the Queen Mother. That's absurd. DNA samples are compared using a procedure known as SDS-PAGE, otherwise known as gel electrophoresis. This produces the familiar chart we know as DNA "fingerprints" - bands of light and dark showing the composition of a DNA sample which has been broken up by enzymes. You cannot examine DNA with a light microscope - you couldn't even do it with a scanning electron microscope.