What If... Doctor Strange Lost His Heart Instead of His Hands? - S1-E4
Plot hole: The episode has wonderful writing from a pure storytelling perspective, however it has zero coherence with the MCU it is supposedly part of. The show was written way before "Loki", for instance, and concepts like "Absolute points" are at odds with it. Likewise, Strange and the Ancient One's powers are radically different (Strange can't foresee the future but can go back at will without rewinding and his mentor can seemingly see past her own death).
What If... Ultron Won? - S1-E8
Plot hole: At the end of the previous episode, the Watcher gets surprised (literally saying "wait, what?") by the arrival of Infinity Ultron inside Party Thor's universe.In this episode we find out the story of Ultron.Ultron realises for the first time that there are other universes to conquer right then because he can'hear' the Watcher talk (to whom?) and goes after him.So the two episodes don't match;Ultron couldn't have reached the other universe "before" his realization, and Uatu is again surprised by it.
What If... Ultron Won? - S1-E8
Plot hole: Ultron cuts through Thanos like butter and acquires the Infinity Stones. He does so after he kills all life on the planet (-2). So Thanos has all the Stones (except Vision/Ultron's) years earlier than normal continuity, for no reason. Not just that; Ultron proceeds then to 'silence' the rest of the universe one planet at a time (which would take forever; Thanos wanted the gems exactly to avoid doing that and make genocide efficient). Amongst those planets, one where he fights The Guardians of the Galaxy, including...Gamora, who should be dead or Thanos could have never got the Soul gem.