What We Owe to Each Other - S1-E6
Jason: [Chidi walks into Jason's bud hole] Oh, hey, homie. Thanks for your advice. I'm about to give Tahani the best gift ever. Check it. [Shows a painting of Frank Caliendo].
Chidi: What?
Jason: She likes impressionist paintings, right? I got her a painting of the best impressionist of all time, Frank Caliendo. He can do it all. Fat Al Pacino, fat Jerry Seinfeld, regular John Madden.
Answer: No, he is fictional. The joke is that, despite being handsome and charming, Larry Hemsworth is so overshadowed by his brothers that nobody else has heard of him and he feels like a failure.