Continuity mistake: In the kitchen, Edith knocks over a bottle filled with green liquid, which shatters and spills on the floor. The aftermath isn't seen in any following shots.
Audio problem: After Gru declines Agnes holding his hand, he slams the door to his house shut. The sound of the door closing is out of sync with it.
Chosen answer: "You have the face of a donkey."
Captain Defenestrator