Other mistake: When Andy places the wedding ring on Serafine's finger after jumping off the Statue of Liberty, he places it on the index finger. Don't people usually put a wedding ring on the ring finger?
Other mistake: During the party in the church near the end the bad guy blocks the church door with a bulldozer. The girl climbs up to the top of the church, breaking off a stone gargoyle which lands on top of the bad guy while he's in the bulldozer. Then the girl climbs back down and gets into the bulldozer, which is completely undamaged from the gargoyle hitting it - the bad guy's body has completely vanished. She manages both climbs impossibly quickly.
Other mistake: Andy (as a wolf) obviously killed the dog in the cemetery because we hear the dog yelping, but in the morning when he's in human form the dog doesn't have teeth marks or a scratch on it, so how did it die?
Other mistake: When you first see the cop she has an English accent, the next time you see her it's a French accent.
Answer: Perhaps the good doc died of a heart attack? Brought on from the horror / terror of being chased and then attacked by a monster? Or some other similar type of affliction. Embolism? Aneurysm?
Alan Keddie