Continuity mistake: During the football game where Jeremy and Sack "tackle" for the second time, Gloria and Mrs. Cleary are startled and jump up from their seats. In one shot Mrs. Cleary's glass is filled about half way with a redish liquor, but in the next it is a hardly visible clear liquid.
Continuity mistake: In the scene when John goes into Jeremy's office to talk about their wedding season; John is holding the cup of water in his right hand, keeping his right hand on cup, but when he throws the cup of water it is then in his left hand.
Chosen answer: The substance is Visine Eye drops which is an old bartender trick for obnoxious drunks. Just a couple of drops in a drink will indeed make the person feel ill.
Damian Torres