Continuity mistake: When Richie is running down the stairs, there's no vomit on left hand, but when he asks for a handshake from the policeman, there is.
Continuity mistake: In the vomitting scene, the young married couple's hotel room door is covered in green slime, but in the next shot it is clean.
Continuity mistake: When Richie gets the pencil shot into his rear, he knocks over the table (which two guests are also sitting at), knocking over all the items on the table. Then Richie and Eddie fight in the kitchen, and it then cuts back to a reaction shot of the two guests sitting at the same table, only now the items on the table are all suddenly back upright and intact again.
Continuity mistake: When the burning crate falls down the stairs, with Rick still in it, how heavily it is burning completely changes between shots.