Revealing mistake: When the old lady falls off her chair, you can see the wire pulling her off. (00:03:35)
Continuity mistake: When the lady arrives at the Thumbtanic, the car has no writing. When the crane picks it up, it says "Sex Scene Car." (00:04:40)
Deliberate mistake: When all the thumbs are at the wall saying "I'm the king of the globe" and "I'm a dentist" you cannot see their legs, so that saved some costume work.
Continuity mistake: When the newscaster is interviewing the lady, as he says, "Spew forth from your lie" (or something like that), he goes from the side of the chair to the middle, between shots.