Continuity mistake: After the two main characters sled down the mountain in that boat, they all fall into the river. In the next shot, they come up from underwater, and the boat miraculously is right-side-up with no water in it.
Continuity mistake: While directors certainly take their liberties with the military, is it reasonable to think that the security would be so lax at a government NBC (nuclear, biological, chemical) research laboratory that you could just kill two guards and walk in and open a cabinet and "hey, there's that super-secret, super-volatile weapon we've been looking for." The military takes their security far more seriously than Hollywood interprets it.
Continuity mistake: During the chase scene on the winding mountain road, the door on the yellow ice cream truck is wide open during the whole chase, except when we see the truck from an aerial view, then we notice that the door is not only closed but locked as well.