Continuity mistake: When Eddie is escaping with Lily from the museum he is on the right hand side of her but in the next shot of them he is now on the left. (01:04:45)
Continuity mistake: In the final underground laboratory explosion scene Keanu Reeves and Rachel Weisz are being pulled up to the surface in a cage by a crane on the surface and are covered with grey soot from the underground explosion. In the ensuing scene when being met by the people on the surface they are all cleaned up.
Continuity mistake: Morgan Freeman and Keanu Reeves meet in Chicago's Field Museum. Reeves runs off screen and suddenly appears in the Museum of Science and Industry clear across town.
Continuity mistake: There is a scene where Keanu Reeves slides down the bridge on his back. In the next scene where he meets Rachel Weisz in train station the camera shows his back. There is nothing wrong with his jacket, it looks like brand new. How's that possible?
Continuity mistake: In the scene where Keanu Reeves and Rachel Wiesz are crossing the lake escaping from Yerkes Observatory, they are on Geneva Lake. However, the shot before they arrive at the house shows a different lake.
Continuity mistake: When Keanu Reeves is walking past the homeless people, a cop car puts its lights and sirens on and proceeds away from where he is. The police car is then seen without its lights on but the sirens still going and coming from the same direction.