Trivia: In the movie, Lou Gehrig concludes his farewell speech with the famous line "I consider myself the luckiest man on the face of the earth". However, in real life, he continued after this point. The last lines of his speech were "And I might have been given a bad break, but I've got an awful lot to live for. Thank you."
Trivia: At the end of the film Lou is seen walking off the field into the dugout. In truth after the speech, Lou had to be helped into the dugout and left the ballpark in a wheelchair.
Trivia: Copper was right handed - all his scenes were filmed right handed and then reversed. The number "4" on the back of his uniform was put on backwards.