Factual error: Even though Pops is in such bad shape that he needs a heart transplant, he isn't hooked up to any monitors or equipment while in the hospital.
Continuity mistake: When Hamilton (the boss at the movie theatre) leaves a message on the answering machine, he mentions that he saw Sam ("Hey, fatso... fatso.") in the TV commercial. However, Sam was never on camera, he was out of sight, opening the trunks by remote control.
Continuity mistake: In the scene where Jack Warden tells Norm MacDonald that he is having a heart attack, you can see that even with them being indoors, it's clearly dark outside. But when the movie cuts to the ambulance taking him to the hospital, it's completely sunny.
Continuity mistake: When Norm Macdonald is thrown out of the window at the bar fight, you can see a perfect outline of broken glass around him.
Continuity mistake: The scene where Sam is mooning the movie line, Mitch stops the car way past the parking meter. But the next shot when Mitch stops and gets out of the car, the camera changes to Sam's butt hanging out the window, but the car is now in front of the parking meter. Sam then opens the door and you see it open past the meter post but the next shot shows the door opening and hitting the post.
Continuity mistake: In the scene where Sam beats up the answering machine and phone with a bat, the phone rings after its knocked off the hook. Then, when Mitch grabs the pieces of the phone to answer it he has the mouthpiece facing the wrong way.
Continuity mistake: After the shot of the meter maid's hood is blown off by the popcorn, it shows a shot of her driving it, hood intact.
Visible crew/equipment: Near the end when you see the skunk humping the dog, you can clearly see the puppeteer's hand moving the skunk.
Revealing mistake: When Norm McDonald points out the movie line and starts honking and Artie Lange is mooning, you can see the motorcycle cops who were used to block traffic.
Audio problem: After the prisoners have their way with Mitch, he says, "The lack of respect, that's what hurts the most. Except for the other thing, that hurts the most." But if you watch his mouth, it is clear that he says something very different.
Continuity mistake: When Sam and Mitch are in Dr. Farthing's office, items on the desk move around depending on the camera angle. Most noticeably, there is a stapler between the heart and pencil holder in one angle and then the pencil holder is right next to the heart in the other angle.
Revealing mistake: When the frat boys from the bar throw Mitch in the dumpster, look at the dumpsters reflection; you can see Norm McDonald/stuntman get a running start and voluntarily jump in.