Audio problem: When Amy first gets into the semi, we can hear her talking to Red but her mouth isn't matching what she is saying.
Revealing mistake: There are no keys in the Jeep when we see the breakdown happen. You can see the steering wheel and where the keys should be. How is this car even moving? (00:08:05 - 00:08:35)
Continuity mistake: When Jeff and Amy run out of the barn and to the truck, there is an angle where it shows the sun already above the horizon, but then the same angle is shown seconds later with Billy chasing them and now the sun hasn't quite risen yet. This is out of sequence.
Character mistake: When Barr denies giving Jeff's wife a ride, Jeff says this was in the last half hour or so - but considering the time it would take the truck to go to Belle's (5 miles away), the wife to call a tow truck, back from Belle's, then Jeff waiting extra time, then fixing the jeep, heading to Belle's, the time he spent inside, then driving along the road until he saw the truck would in no way be only a half hour...more like an hour or two at best.
Suggested correction: Jeff is obviously in distress because he can't find his wife. Is it not possible that because of the stress he's under, the amount of time that has passed is different for him? Besides, we know the wife never made it to Belle's. Later, we see she's been transferred to another vehicle.
Continuity mistake: When Jeff goes to the washroom in the bank, there is a mop/broom handle leaning against the corner of the wall by the door. After he rummages through the cupboard looking for a weapon, the handle is gone.
Revealing mistake: When Kurt Russell is climbing the side of truck you can see a fence revealing that they are parked, even though wind is blowing to make it look like they are moving.