Deliberate mistake: When we are introduced to Jesus, during his slow motion roll, the camera cuts to the ball hitting the pins and then back to Jesus doing a celebratory dance. For some un-known reason, the film of the ball hitting a strike is actually back to front (see the posters above the lane are in mirror image to what they should be). Given that a bowling lane is perfectly symmetrical, if anyone's got an explanation, I'd love to hear it... [Jesus bowls with his right hand. If the scene was played the correct way, you would realize the shot of the ball rolling was done by a LEFT HANDED bowler...so obviously rather than re-shoot the scene with a right-handed bowler they reversed the shot. Voila. Still a mistake but there's why.] (00:25:26)
Deliberate mistake: In the first bowling scene, all the lane numbers are backwards.
Answer: Generally, he means that the boy, Larry Sellers, is disgracing his family (Walter has huge respect for the boy's dad, but considers the kid a dunce). Specifically, Walter is blaming Larry for his father struggling to breathe; that's Larry's dad in an iron lung in the background. Walter and The Dude become louder, more insistent and more vulgar, but the kid still blankly refuses to answer, and all you can hear is the iron lung pumping in the background. Frustrated because the kid isn't intimidated, Walter lashes out: "You're killing your father, Larry!"
Charles Austin Miller