Factual error: The movie takes place in 1843. Dickens is shown to possess a copy of "Varney the Vampire", which is impossible, as it first appeared in serial form in 1845.
Factual error: In the beginning of the movie, during Dickens' visit to America, you can hear them playing the melody from the song "I'm a Yankee Doodle Dandy" written by George M. Cohan in 1904. This was 61 years after the events in the movie. In the ending credits they cite this as "Yankee Doodle Dandy" which was written many years before. But, that was not the melody that was being played.
Factual error: There are references to failures of novels by Dickens that were actually not written until after the events depicted in the film (e.g. Martin Chuzzlewit and Romney and Son).