Factual error: Several times in the film you see astronauts "suit-up" and head straight out the airlock into space. In reality they would have to pre-breathe pure oxygen for forty minutes to purge the nitrogen from their bloodstreams. If they just went straight out they would suffer from "the bends", as divers do.
Factual error: When the super fortress has a near miss with one of the x-plane pilots the pilot should be in free fall and not appearing to float motionless as the super fortress passes by.
Continuity mistake: When Donald Sutherland is getting off the roller coaster to talk to Clint Eastwood. He kisses the woman and then removes his glasses. You then see a shot of the back of his head and his glasses are still on. They then show a shot of his face and they're off.
Continuity mistake: In the opening shot of the NASA people, they are wearing I.D. tags that have the date of 11-99. But just days later Clint Eastwood's tag is a year higher, showing 11-00.
Factual error: After bailing out one of the pilots somehow suspends his free fall and is almost hit by the B29 while motionless in midair.
Visible crew/equipment: When Clint Eastwood first enters IKON to power up the panel, you can see a crew member's hand (with a gold ring) to his right. On his way out you can also see a hand and the top of the head of a crew member in the same location.
Visible crew/equipment: Set lights and camera equipment are reflected in Hawk's sunglasses as he speaks with the kid who wants to go up in his plane.
Continuity mistake: On the reentry James Garner is sitting next to Clint Eastwood - it pans away, then comes back, and no one except Clint Eastwood is in the cockpit. Also one shot shows 4 people in seats during the re-entry.
Factual error: Clint Eastwood and Donald Sutherland go scooting around in open space (admiring a view of Italy on the sunlit side of the Earth) with their gold solar-screen visors retracted wide open. To avoid accidental instant blindness, real astronauts would never open their solar-screen visors during EVA on the sunlit side of the Earth; yet the astronauts in this film do it constantly, with no ill-effects.
Answer: Eastwood would be out on height alone and the rest probably have high blood pressure. https://www.nasa.gov/centers/johnson/pdf/606877main_FS-2011-11-057-JSC-astro_trng.pdf.