Factual error: Jackie is handling medication vials and taking a pill. Some of the vials have childproof "palm and twist" caps, but they were not invented until 1967. (00:48:00 - 00:49:00)
Other mistake: Bobby Kennedy is seen watching television, including a scene that seems to be the shooting of Oswald. However, the Oswald shooting happens about 16 minutes later. (00:41:40 - 00:58:00)