Continuity mistake: Jodie Foster has very blue eyes. When they flashback to her childhood, when she is crossing the lawn to greet her father, the girl playing the young Clarice has dark eyes. (00:20:10)

The Silence of the Lambs (1991)
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Directed by: Jonathan Demme
Starring: Anthony Hopkins, Jodie Foster, Scott Glenn, Ted Levine, Anthony Heald
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Silence of the Lambs is a masterpiece of film-making, as the character of FBI agent Clarice Starling is introduced as a rookie who initiates a terrifying dialog with the sinister cannibal Hannibal Lecter in order to catch the infamous killer Buffalo Bill, who likes to skin his victims. Disturbing yet fascinating movie, by the end you will see why this movie is so admired.
Hannibal Lecter: I do wish we could chat longer, but I'm having an old friend for dinner.
Trivia: In the cage scene right before Hannibal kills and eats the guards, he tells them to roll up the drawings. When the guard is doing that, you can see a copy of Bon Appetit magazine on the table.
Question: Why was Hannibal Lecter so interested in Clarice's past? How would it benefit him?
Answer: Knowing about her past gives him an advantage in how he can manipulate her - he understands her fears, weaknesses, strengths, and so on. A psychiatrist normally deconstructs a patient's psychological make-up to better understand and help them, but in Lecter's case, he uses this knowledge against his victims. However, as he learns about Clarice, he becomes sympathetic and protective toward her.
Answer: Also, he loves psychiatry and analyzing people. He is bored in his cell and this is a chance to do something he enjoys a lot.
Answer: Clarice's answers also enable Lecter to assess her honesty/ integrity and sincerity, as well as ascertain if she is trustworthy - or even worthy - enough for him to reveal certain kinds of information.
Answer: I remember a scene where he seems to roll his eyes in a kind of ecstasy as he comprehends, then thanks her, and shortly after touches her hand as he passes the folder. "People will say we're in love."
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Suggested correction: Eye color also can change with age. This happens in 10 to 15 percent of the Caucasian population (people who generally have lighter eye colors).
Babies born with blue eyes can develop brown or darker eyes as melanin is produced. And while eye color can get lighter with age (older than Clarice usually), a child her age with brown eyes won't develop blue eyes. They could turn green maybe, but not the blue color seen.
Bishop73
I just rewatched the scene you were talking about and they're not blue eyes they're actually hazel and the adult Clarice could be wearing contact lenses.
Joey221995