Trivia: The character of Kagan, the shaved head guy with the beard, is played by Jean-Claude Van Damme's son, Kris Van Damme.
Trivia: It might seem bizarre to make a movie about a 90-year-old drug mule (transporter), but "The Mule" is actually based on the true story of Leo Sharp who became known as the oldest drug mule in the U.S. Whereas Leo Sharp was a World War II veteran, Earl Stone in the movie was a Korean War veteran - and Clint Eastwood ("Earl") really did serve during the Korean War.
Trivia: At the very end Paul points at a guy on the street with his finger as a gun just like Charles Bronson did in the 1974 version.
Trivia: The protagonist browses the archives of local newspapers to research more into the fire of May 3rd 2003. The news at the very top right of the front page, by the title "Town treasurer celebrates his re-election after disputed elections" features a mugshot of the director of the movie, Paul Feig. (01:20:25)