Character mistake: On two occasions throughout the film, Kraven's accent changes - once when he is talking to Lucian near the beginning of the movie and near the end of the movie when he is telling Selene that Viktor killed her family.
Character mistake: Although Dr. Kalarjian said that there is a "code blue", which means a patient requiring resuscitation or other immediate medical attention, she wanders over there without rushing at all.
Suggested correction: When she was getting closer, she started rushing more. It took a while for her to get there but maybe that was just done to fool the audience. Kimberly did think she was going to kill Isabella after all.
Character mistake: There was no chance of Will and Lori knowing what's happening with Mark in the house. Neither him nor anyone else called them. So what made them rush home with van, after they've been casually driving in their previous scene?
Character mistake: There's no way that using a regular needle and thread to sew up that wound would work the way it's shown. Anybody who knew what they were doing - which John Cusack is portrayed as knowing - would also know that using unsterilized materials and instruments without a sterile field from an uncleaned massive open wound is a great way to kill your patient.
Suggested correction: The main plot of this film takes place inside the head of a murderer with dissociative identity disorder. The fact that stitching up a wound in that matter wouldn't work is irrelevant to the fact that it is how Malcolm is playing out the scenario in his head.
You're making a good point to invalidate a "character mistake", but couldn't the entry be reclassified as a "factual mistake" and stand as written?
Character mistake: The Cadillac is identified by Robby as a '57 Eldorado. It's actually a '57 Series 75 Limousine.
Character mistake: Remy mentions that the insects are part ant, cockroach and termite. She dismisses the mantis side, which allows it to mimic.
Character mistake: The very advanced computer on the plane can't spell, since it infers probabilities that a member of the crew has been "INFECTETED" by the creature. (01:06:40)
Character mistake: When Duddit's mom is packing his lunchbox, she refers to him as "Henry". (01:45:54)