Continuity mistake: When the class is in Arnold's esophagus, Tim says something, then it cuts back to Ms. Frizzle. Arnold is sitting in the back seat of the bus.
Neogenic Nightmare Chapter 5: Mutants Revenge - S2-E5
Continuity mistake: When Spider-Man says "I get the picture, Wolvie," he is shown to be running. When the shot changes, he is walking. (00:04:05)
Coach Fussell's Lament - S2-E5
Continuity mistake: Chairface and Chrome Dome arrive at the Brianchild's house in the same car, but drive off in separate cars.