Continuity mistake: When the prostitute is reflected in the mirror, her kimono bares one of the shoulders. She turns, and both shoulders are covered. (00:08:55)
Other mistake: In the opening credits, the composer of the movie score is credited as "Elizabeth Lutyens", with a Z. Her proper name was Elisabeth, with an S. (00:00:50)
Continuity mistake: During the second solitary visit that the Native Girl pays to doctor Bwana, she has to hold him steady after he drank the torpedo juice. Her right hand is in a completely different position in the various shots, and she lets Buster Keaton go once but is still holding him after the cut.
Factual error: Rifles and more so, cannons of the type shown in the movie were not close to being invented in the 1500s.
Continuity mistake: In the animal mortuary, Robert Morse opens a refrigerator with two dogs in it as he reads from a book. When he returns to that same refrigerator seconds later, the dogs are gone, replaced by a crumpled white cloth and a cat. (01:01:30)
Other mistake: Dean Jones and Connie Stevens are riding in a gondola of a skyway ride at a seaside amusement park. The gondola they are in is obviously on a studio soundstage. It is much larger than the gondolas shown in the rear-screen projection. In addition, there are no riders in any of the other gondolas and the gears and cables of the ride make absolutely no sound.
Revealing mistake: When Phil kills himself by throwing himself off the roof, in the shot of him supposedly hitting the ground it is painfully obvious that it is a dummy. Not only does it hit the ground completely rigidly but the wig on it even noticeably flies off on impact.