Trivia: Spider-Man creator Stan Lee makes his standard cameo appearance for this film when Spider-Man and Doc Ock are fighting on the side of the building. The first shot of the street during the fight shows a woman being pushed out of the way as some debris falls; the man pushing her is Lee.
Trivia: On Burt Reynolds' hat is the shape of Florida with a star. The star marks the location of Jupiter, where Reynolds lived much of his life, had a ranch, and eventually passed away.
Trivia: S.E. Hinton, the author of "The Outsiders", has a cameo in the scene where Johnny is lying on his stomach in hospital, playing the nurse tending to Dally who says "what did you do with your gown?"
Trivia: Ron Howard's father, Rance, makes a cameo as one of the Cardinals locked in conclave. (00:32:10)