Character mistake: Dwanye Johnson is called onto the ice, the first thing he does is throws a player through a glass pane. The player looses a tooth. The close up shows that the tooth is a molar, but the commentators say, seconds later, "Ohhh that's an incisor!" (00:01:00 - 00:02:35)
Character mistake: After Gru tucks the girls in for the night, Dr. Nefario tells him that there are 48 hours until the rocket's scheduled launch. The rocket launch, then, should have taken place at night, around the time the girls go to bed, two days later. The rocket, however, launches during daylight hours.