Other mistake: When Frenzy attacks Sam, the teenager wears straight leg jeans with a narrow leg opening (not boot cut) and thick-soled Nikes, seen in numerous shots, as he kicks at the Decepticon. After the cut to Mikaela (who finds the reciprocating saw), during which Frenzy has already pulled off the bottom of Sam's jeans, Sam continues to kick and scream just before he gets up and runs. Problem is Sam still wears both thick-soled Nikes, neither of which slipped off as Frenzy maniacally pulled the jeans, with narrow leg openings, from his kicking legs/feet. Impossible even in the best of circumstances.
Other mistake: When Leela is signing the petition, Amy grows a third arm for a split second.
Other mistake: The dead blonde whose "throat was slit" is shown up-close twice (once in real time and once in a crime photo) and her neck is unharmed, with blood only underneath her head.
Other mistake: Right at the beginning of the movie, when Lewis's real mum picks him up from the box and hugs him, it's no more than three seconds before she hears Lewis from the future slipping on the step. She gets scared and puts baby Lewis back in the box. When Wilbur takes Lewis to meet his mum, near the end of the movie, the time his mum holds the baby is more than twenty five seconds.
Other mistake: In the scene when Robert gets caught up in the trap by Grand Central Terminal, there are no traffic lights on the upper street that they show him being suspended from.
Other mistake: In the scene where Dr. Isaacs is in the teleconference with the Umbrella Board of Directors, there are several glasses of water sitting in front of each individual hologram. At the end of the teleconference, the holograms of the board members disappear, but none of the glasses follow suit. This tells us that the glasses of water were physically in the room with Dr. Isaacs, for absolutely no reason, given all the other attendees weren't really there. (00:17:40)
Other mistake: Considering Peter's strength and anger plus power of the symbiote, there is no way that Mary Jane would be completely unscathed after he accidentally hit her.
Other mistake: After Dark Superman kills Toyman, someone calls Lois and tells her that. She answers the phone and says "Lane... HE DID WHAT!?" She responds to the news way too quickly. There wasn't even enough time for the person on the other end to say anything, much less inform Lois that Superman killed someone. (00:48:55)
Other mistake: Towards the end of the film, as the two kids are escaping through the subway being guided through the night vision scope used by the army major, they are virtually blind and have to pick their way through dead bodies, escalators etc. This seems a bit unnecessary as the M4 rifle to which the night vision scope is attached also has a torch attached to the RIS rail. Military spec torches are extremely bright - why not just turn it on? They can't be worried about being spotted, because they are shouting at each other, not concerned with what might spot them.
Other mistake: When Wray goes to save Cherry from the hospital, he puts on latex gloves to stab the infected. But after he gets Cherry, he stabs a zombie with his bare hands. (00:51:15 - 00:53:25)