Continuity mistake: The morning after the second party, the items on the coffee table change instantly between shots. Several beer bottles and blue cups vanish, whilst a red cup and red bowl appear. (00:11:00)
Continuity mistake: At the diner, before Mrs. Duncan comes to confess about murdering her husband, Brennan takes a sip of tea. Her glass at this point is less than half full. When Mrs. Duncan walks in, the same glass is now almost full.
Continuity mistake: When Izzie is looking at the patient board, there are some lines on it which have been wiped out. But in the next scene we actually see Meredith walk to the board and wipe these exact same lines off (even though they were previously rubbed out...) (00:34:05)