Factual error: In a number of episodes people are shown eating and drinking in the laboratories. For instance, in "Miss Willows' Regrets" Nick and Greg are seen eating fried chicken in the lab, and in "Overload" Sara eats a sandwich while watching Grissom experiment with her deli pickle. There are other examples. No reputable laboratory (which this is supposed to be) would allow its staff to eat or drink while in the lab. It is basic scientific protocol to prevent contamination of samples or the person picking up toxins on their food.
Factual error: Darien sets up a tripod and videotapes himself leaving a message for the Agency. When the tape is played back later, the camera can be seen to have both zoomed in and panned to follow his movements, even though no one was there to make those adjustments. (00:30:30)
Factual error: The map of the western United States shown during the weather report at the start of the episode shows some states drawn incorrectly. Idaho's entire western border is a straight line, whereas in real life, Oregon has a horn-shaped indentation on its northeastern border that it shares with Idaho. Idaho also looks like a crude staircase, with the southwestern border of Montana going down to central Wyoming, whereas that area in real life is around the northwestern part of Wyoming.