Factual error: In a number of episodes people are shown eating and drinking in the laboratories. For instance, in "Miss Willows' Regrets" Nick and Greg are seen eating fried chicken in the lab, and in "Overload" Sara eats a sandwich while watching Grissom experiment with her deli pickle. There are other examples. No reputable laboratory (which this is supposed to be) would allow its staff to eat or drink while in the lab. It is basic scientific protocol to prevent contamination of samples or the person picking up toxins on their food.
Factual error: Darien sets up a tripod and videotapes himself leaving a message for the Agency. When the tape is played back later, the camera can be seen to have both zoomed in and panned to follow his movements, even though no one was there to make those adjustments. (00:30:30)
Factual error: After Alex is dragged underwater by the harness tether, Scott goes swimming after him and easily locates him. Given that they are in the middle of the ocean at nighttime during a heavy rainstorm, and Scott is wearing sunglasses, it would be way too dark below the surface to see anything.