The Curious Tale of Mr Spearfish - S3-E1
Character mistake: The whole mystery kicks off when Creek sees a photograph of Alice Spearfish with her parents, and concludes that she is adopted because two people with brown eyes cannot have a child with blue eyes. An obsessive polymath like Creek must surely know that that is wrong. The genetics are complex and though uncommon it is possible for a couple with brown eyes to have a child with blue eyes and the other way around.
Character mistake: When the zombies break into Buffy's house, she stakes one to check if it's a vampire. But she should know full well that it isn't a vampire as they all broke into her house without being invited.
Ghost Passenger Ship Murder Case: File 2 - S2-E6
Character mistake: During Wakaouji's flashback, if he really picked the picture from his breast pocket the way it is depicted, then the picture he showed to the captain was upside down. Would be kinda hilarious, but I don't think that is what the animators were going for. (00:16:35)
Character mistake: When Walker and Satch are in the car looking for Walker's son, Walker tells Satch his son is 17. Afterward, when they are out on the streets, Walker asks some people if they have seen his 18-year old son.
Suggested correction: Jonathan actually states it's a photo of 2 blue eyed parents and a brown eyed daughter.
Which is still possible! It isn't even uncommon. Brown eyed parents can have a blue eyed child and vice versa - that's what recessive genes are all about.