The Post-Modern Prometheus - S5-E5
[After spilling coffee on his lap.]
Mulder: Great, now my crotch will be up all night.
Penhaligon: To be left at the airport, Fitz, that's one thing. But to be left by a big, fat, egocentric, middle-aged man, well, that's a different thing altogether.
Fitz: I didn't mind the big.