Factual error: Ryan, the laboratory technician, eats his lunch of burger and fries while discussing a murder case with Assistant D.A. Claire Kincaid. Trouble is, they are in his laboratory. No lab technician ever, ever eats or drinks in a laboratory - it is the most basic lab protocol imaginable. He could contaminate his samples in any one of a hundred ways, he inevitably contaminates his gloves or fingers with residue from his meal and he risks poisoning himself with accidental transfer. This is not a character error - lab security is hammered into science students starting with the first day of first year and number one on the list is never, ever eat or drink in your lab.
Episode Nine - S2-E2
Continuity mistake: The necklace James took from the coconut in Dr. Jacobi's office in the previous episode had a gold chain. When he gives it to Agent Cooper in this episode, it's on leather.