Trivia: Paul Reiser's character Carter Burke was so immediately hated that during the movie's premiere his sister hit him, and when Burke's death occurred, his mom's response was simply "good."
Trivia: In the final confrontation between Dollarhyde and Graham, Tom Noonan had to lie in a pool of stage blood for several hours as the crew worked on other shots. After all this time, the stage blood dried into a thick, cement-like adhesive that all but fused Noonan to the carpet.
Trivia: The film's director, David Cronenberg, has a cameo in this film as the doctor who helps Ronnie deliver her maggot baby.
Trivia: As an homage to a certain legendary horror actor, the cornershop at which Tommy phones Megan Garris (Jennifer Cooke) is called Karloff's General Store, after Boris Karloff.
Trivia: Both Richard Lawson and Beatrice Straight were approached to reprise their roles from the first film (as members of the paranormal team that helped the family and Tangina), both both had to turn down the chance. Lawson was busy on another project and Straight was reportedly quite ill at the time of the shoot, and didn't feel up to filming anything.
Trivia: The set of the "Big Boy" explosion is still sitting in the middle of the jungle of Belize. It has remained virtually untouched since filming.
Trivia: After the six wires are cut to defuse the weapon, you can see the amount of time left on the clock is 07:16:45, which is the date of the first successful test of the Atomic Bomb.
Trivia: Diana Scarwid ab-libbed the famous opening line, "There is no God!".
Trivia: Kristy Swanson received coaching from a professional mime in order to properly move like a cyborg.