Trivia: Paul Reiser's character Carter Burke was so immediately hated that during the movie's premiere his sister hit him, and when Burke's death occurred, his mom's response was simply "good."
Trivia: In the final confrontation between Dollarhyde and Graham, Tom Noonan had to lie in a pool of stage blood for several hours as the crew worked on other shots. After all this time, the stage blood dried into a thick, cement-like adhesive that all but fused Noonan to the carpet.
Trivia: The film's director, David Cronenberg, has a cameo in this film as the doctor who helps Ronnie deliver her maggot baby.
Trivia: As an homage to a certain legendary horror actor, the cornershop at which Tommy phones Megan Garris (Jennifer Cooke) is called Karloff's General Store, after Boris Karloff.
Trivia: Unbeknownst to the cast and crew, several of the skeletons ordered for the production were real human skeletons (as opposed to replicas). When this was discovered, some crew and cast members demanded an exorcism or cleansing be performed on set, as they had already been feeling uneasy on-set before learning this, and felt the real skeletons may have brought some unwanted spirits to the set. Co-star Will Sampson, who like his character was a real-life shaman, offered to return to set one night after everyone else went home in order to perform an exorcism ritual. Reportedly, the mood and feeling on set greatly improved afterwards.
Trivia: The set of the "Big Boy" explosion is still sitting in the middle of the jungle of Belize. It has remained virtually untouched since filming.
Trivia: Kristy Swanson received coaching from a professional mime in order to properly move like a cyborg.
Trivia: After the six wires are cut to defuse the weapon, you can see the amount of time left on the clock is 07:16:45, which is the date of the first successful test of the Atomic Bomb.
Trivia: Diana Scarwid ab-libbed the famous opening line, "There is no God!".