Plot hole: It's assumed that Dr. No had Professor Dent slip the spider into Bond's hotel room that night but if it were that easy to do that then why not just hide an assassin in the room to begin with. Someone had to be in the room to tamper with Bond's briefcase, the closet, and possibly the bottle of liquor so just hide an assassin instead of waiting for the spider to kill Bond. (00:40:00)