Trivia: Julie Delpy admitted that the only reason that she did this movie was because she needed to pay her rent.
Trivia: When this movie was released to DVD in Australia, the ending had Andy running to the hospital where Seraphine had just given birth to Andy's child. The baby opens its eyes and the eyes are yellow, indicating that the baby is a werewolf. Later DVD releases had the ending where Andy and Seraphine bungee jump off the Statue of Liberty.
Trivia: The original script for this movie had Andy going to Paris after learning his Uncle had been attacked, there was no secret werewolf society but Claude would still be a werewolf and the main antagonist, there was no drug that cause an instant transformation into a werewolf; instead, there would be a specific plant that allowed Claude to change into a werewolf any time he wanted to and Serafine would have been the werewolf that attacked and bit Andy.
Trivia: In a scene that was deleted from the movie, Claude reveals that the werewolf society had been around for centuries and that the werewolf who attacked David Kessler in "An American Werewolf In London" was a member.
Answer: Perhaps the good doc died of a heart attack? Brought on from the horror / terror of being chased and then attacked by a monster? Or some other similar type of affliction. Embolism? Aneurysm?
Alan Keddie