Trivia: This film will actually have the shortest amount of time elapsed between installments, releasing around 2 years and 4 months after Ghostbusters: Afterlife. Ghostbusters 2 released 5 years after the original film, the 2016 film released 27 years after Ghostbusters 2, and Ghostbusters: Afterlife released 5 years after the 2016 film.
Trivia: This is the first MCU film since 2008's The Incredible Hulk to feature Liv Tyler as Betty Ross and Tim Blake Nelson as Samuel Sterns a.k.a. The Leader. They were the last two of that film's five main characters to reappear in the franchise.
Trivia: Michael Keaton said at Cinemacon 2024 that this was the most fun he ever had making a film.
Trivia: Ryan Gosling showed up to the premiere of this film dressed as Beavis from Beavis and Butt-Head. He had previously dressed up as the character a few weeks prior for an episode of Saturday Night Live, alongside SNL cast member Mikey Day, who was dressed as Butt-Head.
Trivia: Chip, who plays the role of Alfie (Ellie's cat), is the pet cat of Claudia Schiffer, the wife of the film's director, Matthew Vaughn.
Trivia: Because this film went into production during the midst of the Writers' Guild strike, Ryan Reynolds, as one of the film's writers, was not allowed to ad-lib his dialogue on set.
Trivia: The wallpaper in the hotel room, where the girls spend the night after the diner incident, matches the carpet in the hotel from The Shining.
Trivia: The restaurant near the bookstore where Charlie works is called the Double Deuce. Double Deuce was the name of the Road House in the 1989 film version.